PMID:10947842
| Citation |
Matsubara, M, Kitaoka, SI, Takeda, SI and Mizuno, T (2000) Tuning of the porin expression under anaerobic growth conditions by his-to-Asp cross-phosphorelay through both the EnvZ-osmosensor and ArcB-anaerosensor in Escherichia coli. Genes Cells 5:555-69 |
|---|---|
| Abstract |
Widespread bacterial signal transduction circuits are generally referred to as 'two-component systems' or 'histidine (His)-to-aspartate (Asp) phosphorelays.' In Escherichia coli, as many as 30 distinct His-to-Asp phosphorelay signalling pathways operate in response to a wide variety of environmental stimuli, such as medium osmolarity and anaerobiosis. In this regard, it is of interest whether or not some of them together constitute a network of signalling pathways through a physiologically relevant mechanism (often referred to as 'cross-regulation'). We have addressed this issue, with special reference to the osmo-responsive EnvZ and anaero-responsive ArcB phosphorelay signalling pathways in E. coli. |
| Links | |
| Keywords |
Anaerobiosis; Aspartic Acid/physiology; Bacterial Outer Membrane Proteins/physiology; Bacterial Proteins/physiology; Electrophoresis, Polyacrylamide Gel; Escherichia coli/physiology; Escherichia coli Proteins; Gene Expression; Genetic Complementation Test; Genetic Vectors; Histidine/physiology; Membrane Proteins/physiology; Multienzyme Complexes/physiology; Phosphorylation; Porins/metabolism; Protein Kinases/physiology; Recombinant Proteins; Signal Transduction/physiology; Water-Electrolyte Balance; beta-Galactosidase/biosynthesis |
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