PMID:10913097
| Citation |
Ibañez, E, Gimenez, R, Pedraza, T, Baldoma, L, Aguilar, J and Badia, J (2000) Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose. J. Bacteriol. 182:4625-7 |
|---|---|
| Abstract |
Genes yiaP and yiaR of the yiaKLMNOPQRS cluster of Escherichia coli are required for the metabolism of the endogenously formed L-xylulose, whereas yiaS is required for this metabolism only in araD mutants. Like AraD, YiaS was shown to have L-ribulose-5-phosphate 4-epimerase activity. Similarity of YiaR to several 3-epimerases suggested that this protein could catalyze the conversion of L-xylulose-5-phosphate into L-ribulose-5-phosphate, thus completing the pathway between L-xylulose and the general metabolism. |
| Links | |
| Keywords |
Carbohydrate Epimerases/genetics; Carbohydrate Epimerases/metabolism; Escherichia coli/genetics; Escherichia coli/metabolism; Genetic Complementation Test; Multigene Family; Mutagenesis; Operon; Restriction Mapping; Xylulose/biosynthesis; Xylulose/metabolism |
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