PMID:10886362

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Citation

Hiraga, S, Ichinose, C, Onogi, T, Niki, H and Yamazoe, M (2000) Bidirectional migration of SeqA-bound hemimethylated DNA clusters and pairing of oriC copies in Escherichia coli. Genes Cells 5:327-41

Abstract

We previously found that SeqA protein, which binds preferentially to newly replicated hemimethylated DNA, is localized as discrete fluorescent foci in Escherichia coli cells. A single SeqA focus, localized at midcell, separates into two foci and these foci migrate abruptly in opposite directions.

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Keywords

Bacterial Outer Membrane Proteins; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Biological Transport/genetics; DNA Methylation; DNA Replication; DNA, Bacterial/genetics; DNA, Bacterial/metabolism; DNA-Binding Proteins/genetics; Escherichia coli/genetics; Escherichia coli Proteins; Origin Recognition Complex; Transcription Factors; Viral Proteins/genetics

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