PMID:10858262
| Citation |
Lai, XH, Arencibia, I, Johansson, A, Wai, SN, Oscarsson, J, Kalfas, S, Sundqvist, KG, Mizunoe, Y, Sjöstedt, A and Uhlin, BE (2000) Cytocidal and apoptotic effects of the ClyA protein from Escherichia coli on primary and cultured monocytes and macrophages. Infect. Immun. 68:4363-7 |
|---|---|
| Abstract |
Cytolysin A (ClyA) is a newly discovered cytolytic protein of Escherichia coli K-12 that mediates a hemolytic phenotype. We show here that highly purified ClyA and ClyA-expressing E. coli were cytotoxic and apoptogenic to fresh as well as cultured human and murine monocytes/macrophages. |
| Links | |
| Keywords |
Animals; Apoptosis/drug effects; Cell Death/drug effects; Cell Line; DNA Fragmentation/drug effects; Escherichia coli/genetics; Escherichia coli/pathogenicity; Escherichia coli Proteins; Hemolysin Proteins/genetics; Hemolysin Proteins/isolation & purification; Hemolysin Proteins/toxicity; Humans; Macrophages/drug effects; Macrophages/pathology; Mice; Monocytes/drug effects; Monocytes/pathology; U937 Cells |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
See also
References
See Help:References for how to manage references in EcoliWiki.