PMID:10792463
| Citation |
Gulati, A and Mahadevan, S (2000) Mechanism of catabolite repression in the bgl operon of Escherichia coli: involvement of the anti-terminator BglG, CRP-cAMP and EIIAGlc in mediating glucose effect downstream of transcription initiation. Genes Cells 5:239-50 |
|---|---|
| Abstract |
Expression of the bgl operon of Escherichia coli, involved in the regulated uptake and utilization of aromatic beta-glucosides, is extremely sensitive to the presence of glucose in the growth medium. We have analysed the mechanism by which glucose exerts its inhibitory effect on bgl expression. |
| Links | |
| Keywords |
Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Cyclic AMP/metabolism; Cyclic AMP/pharmacology; Cyclic AMP Receptor Protein/genetics; Cyclic AMP Receptor Protein/metabolism; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli Proteins; Gene Expression Regulation, Bacterial/drug effects; Glucose/pharmacology; Glucosides/metabolism; Membrane Proteins/genetics; Operon; Phosphoenolpyruvate Sugar Phosphotransferase System/genetics; Phosphoenolpyruvate Sugar Phosphotransferase System/metabolism; Phosphorylation/drug effects; Protein Kinases/genetics; RNA-Binding Proteins/genetics; RNA-Binding Proteins/metabolism; Terminator Regions, Genetic; Transcription, Genetic |
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