PMID:10772854

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Citation

Yoshida, T, Obata, N and Oosawa, K (2000) Color-coding reveals tandem repeats in the Escherichia coli genome. J. Mol. Biol. 298:343-9

Abstract

Genomic DNA contains a wide variety of repetitive sequences. In Escherichia coli, there have been several classes of repetitive sequences reported, some of which cluster as tandem repeats. We propose a novel method for analyzing symbolic sequences by two-dimensional pattern formation with color-coding. We applied this method for searching tandem repeats in the E. coli genome and found approximately 50 repeats with periods longer than 30 bases. The longest repeat has a period of 1267 bases.

Links

PubMed Online version:10.1006/jmbi.2000.3667

Keywords

Base Sequence; Color; Computational Biology/methods; DNA, Bacterial/genetics; Escherichia coli/genetics; Genome, Bacterial; Molecular Sequence Data; Pattern Recognition, Automated; Sequence Analysis, DNA/methods; Tandem Repeat Sequences/genetics

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