PMID:10762278
| Citation |
Monterrubio, R, Baldoma, L, Obradors, N, Aguilar, J and Badia, J (2000) A common regulator for the operons encoding the enzymes involved in D-galactarate, D-glucarate, and D-glycerate utilization in Escherichia coli. J. Bacteriol. 182:2672-4 |
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| Abstract |
Genes for D-galactarate (gar) and D-glucarate (gud) metabolism in Escherichia coli are organized in three transcriptional units: garD, garPLRK, and gudPD. Two observations suggested a common regulator for the three operons. (i) Their expression was triggered by D-galactarate, D-glucarate, and D-glycerate. (ii) Metabolism of the three compounds was impaired by a single Tn5 insertion mapped in the yaeG gene (proposed name, sdaR), outside the D-galactarate and D-glucarate systems. Expression of the sdaR gene is autogenously regulated. |
| Links | |
| Keywords |
Chromosome Mapping; Cloning, Molecular; Escherichia coli/enzymology; Escherichia coli/genetics; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Regulator; Glucaric Acid/metabolism; Glyceric Acids/metabolism; Operon; Sugar Acids/metabolism; Transcription, Genetic |
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