PMID:10745001
| Citation |
Hoch, JA (2000) Two-component and phosphorelay signal transduction. Curr. Opin. Microbiol. 3:165-70 |
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| Abstract |
Two-component and phosphorelay signal transduction systems are the major means by which bacteria recognize and respond to a variety of environmental stimuli. Recent results have implicated these systems in the regulation of a variety of essential processes including cell-cycle progression, pathogenicity, and developmental pathways. Elucidation of the structures of the interacting domains is leading to an understanding of the mechanisms of molecular recognition and phosphotransfer in these systems. |
| Links | |
| Keywords |
Bacteria/enzymology; Bacteria/growth & development; Bacteria/metabolism; Bacteria/pathogenicity; Bacterial Proteins/chemistry; Bacterial Proteins/metabolism; Genes, Regulator/physiology; Phosphorylation; Protein Kinases/chemistry; Protein Kinases/metabolism; Protein Structure, Tertiary; Signal Transduction; Transcription Factors/chemistry; Transcription Factors/metabolism |
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