PMID:10713416
| Citation |
Kitagawa, M, Matsumura, Y and Tsuchido, T (2000) Small heat shock proteins, IbpA and IbpB, are involved in resistances to heat and superoxide stresses in Escherichia coli. FEMS Microbiol. Lett. 184:165-71 |
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| Abstract |
To investigate the function of Escherichia coli small heat shock proteins, IbpA and IbpB, we constructed ibpA-, ibpB- and ibpAB-overexpressing strains and also an ibpAB-disrupted strain. The ibpA-, ibpB- and ibpAB-overexpressing strains were found to be resistant not only to heat but also to superoxide stress. However, the ibpAB-disrupted strain was not more sensitive to these stresses than the wild-type strain. The heat sensitivity of a rpoH amber mutant was partially suppressed by the overexpression of plac::ibpAB. These results suggest that IbpA and IbpB may be involved in the resistances to heat and oxidative stress. |
| Links | |
| Keywords |
Escherichia coli/genetics; Escherichia coli/physiology; Escherichia coli Proteins; Gene Deletion; Heat-Shock Proteins/genetics; Heat-Shock Proteins/physiology; Hot Temperature; Hydrogen Peroxide/pharmacology; Oxidative Stress; Paraquat/pharmacology; Plasmids/genetics; Sigma Factor; Superoxides/pharmacology; Transcription Factors/genetics |
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