PMID:10707066

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Citation

de la Cruz, F and Davies, J (2000) Horizontal gene transfer and the origin of species: lessons from bacteria. Trends Microbiol. 8:128-33

Abstract

In bacteria, horizontal gene transfer (HGT) is widely recognized as the mechanism responsible for the widespread distribution of antibiotic resistance genes, gene clusters encoding biodegradative pathways and pathogenicity determinants. We propose that HGT is also responsible for speciation and sub-speciation in bacteria, and that HGT mechanisms exist in eukaryotes.

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Keywords

Bacteria/genetics; Bacteria/metabolism; Bacteria/pathogenicity; Biodegradation, Environmental; Drug Resistance, Microbial; Evolution, Molecular; Recombination, Genetic; Virulence

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