PMID:10673430

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Citation

Schneider, G, Käck, H and Lindqvist, Y (2000) The manifold of vitamin B6 dependent enzymes. Structure 8:R1-6

Abstract

Pyridoxal-5'-phosphate (vitamin B6) binding enzymes form a large superfamily that contains at least five different folds. The availability of an increasing number of known three-dimensional structures for members of this superfamily has allowed a detailed structural classification. Most progress has been made with the fold type I or aspartate aminotransferase family.

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Keywords

Alanine Racemase/chemistry; Alanine Racemase/metabolism; Alanine Transaminase/chemistry; Alanine Transaminase/metabolism; Animals; Aspartate Aminotransferases/chemistry; Aspartate Aminotransferases/metabolism; D-Alanine Transaminase; Enzymes/chemistry; Enzymes/metabolism; Humans; Phosphorylases/chemistry; Phosphorylases/metabolism; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxine/metabolism; Tryptophan Synthase/chemistry; Tryptophan Synthase/metabolism

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