PMID:10611671
| Citation |
Doolittle, WF (1999) Lateral genomics. Trends Cell Biol. 9:M5-8 |
|---|---|
| Abstract |
More than 20 complete prokaryotic genome sequences are now publicly available, each by itself an unparalleled resource for understanding organismal biology. Collectively, these data are even more powerful: they could force a dramatic reworking of the framework in which we understand biological evolution. It is possible that a single universal phylogenetic tree is not the best way to depict relationships between all living and extinct species. Instead a web- or net-like pattern, reflecting the importance of horizontal or lateral gene transfer between lineages of organisms, might provide a more appropriate visual metaphor. Here, I ask whether this way of thinking is really justified, and explore its implications. |
| Links | |
| Keywords |
Evolution, Molecular; Genome; Phylogeny; Prokaryotic Cells/classification; RNA, Ribosomal/classification |
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