PMID:10574789
| Citation |
Mondragón, A and DiGate, R (1999) The structure of Escherichia coli DNA topoisomerase III. Structure 7:1373-83 |
|---|---|
| Abstract |
DNA topoisomerases are enzymes that change the topology of DNA. Type IA topoisomerases transiently cleave one DNA strand in order to pass another strand or strands through the break. In this manner, they can relax negatively supercoiled DNA and catenate and decatenate DNA molecules. Structural information on Escherichia coli DNA topoisomerase III is important for understanding the mechanism of this type of enzyme and for studying the mechanistic differences among different members of the same subfamily. |
| Links | |
| Keywords |
Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; DNA Topoisomerases, Type I/chemistry; DNA Topoisomerases, Type I/metabolism; DNA-Binding Proteins/chemistry; DNA-Binding Proteins/metabolism; Escherichia coli/enzymology; Models, Molecular; Molecular Sequence Data; Protein Conformation; Sequence Homology, Amino Acid |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.