PMID:10498949

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Citation

Alekshun, MN and Levy, SB (1999) The mar regulon: multiple resistance to antibiotics and other toxic chemicals. Trends Microbiol. 7:410-3

Abstract

The chromosomal multiple antibiotic resistance (mar) locus of Escherichia coli and other members of the Enterobacteriaceae controls resistance to multiple, structurally unrelated compounds including antibiotics, household disinfectants, organic solvents and other toxic chemicals. The Mar phenotype is induced following exposure to a variety of chemicals with aromatic rings.

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Keywords

Anti-Bacterial Agents/pharmacology; Disinfectants/pharmacology; Drug Resistance, Microbial/genetics; Drug Resistance, Multiple/genetics; Escherichia coli/drug effects; Escherichia coli/genetics; Humans; Regulon; Solvents/pharmacology

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