PMID:10089491

Citation	Hubbard, TJ, Ailey, B, Brenner, SE, Murzin, AG and Chothia, C (1998) SCOP, Structural Classification of Proteins database: applications to evaluation of the effectiveness of sequence alignment methods and statistics of protein structural data. Acta Crystallogr. D Biol. Crystallogr. 54:1147-54
Abstract	The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of all known protein structures. The classification is on hierarchical levels: the first two levels, family and superfamily, describe near and far evolutionary relationships; the third, fold, describes geometrical relationships. The distinction between evolutionary relationships and those that arise from the physics and chemistry of proteins is a feature that is unique to this database, so far. The database can be used as a source of data to calibrate sequence search algorithms and for the generation of population statistics on protein structures. The database and its associated files are freely accessible from a number of WWW sites mirrored from URL http://scop. mrc-lmb.cam.ac.uk/scop/.
Links	PubMed
Keywords	Algorithms; Amino Acid Sequence; Database Management Systems; Databases, Factual; Evaluation Studies as Topic; Molecular Sequence Data; Protein Conformation; Protein Folding; Sequence Alignment/methods; Sequence Alignment/standards
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