PMID:10068995
| Citation |
Horst, JP, Wu, TH and Marinus, MG (1999) Escherichia coli mutator genes. Trends Microbiol. 7:29-36 |
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| Abstract |
The isolation and characterization of Escherichia coli mutator genes have led to a better understanding of DNA replication fidelity mechanisms and to the discovery of important DNA repair pathways and their relationship to spontaneous mutagenesis. Mutator strains in a population of cells can be beneficial in that they allow rapid selection of variants during periods of stress, such as drug exposure. |
| Links | |
| Keywords |
DNA Repair; Escherichia coli/genetics; Escherichia coli/growth & development; Escherichia coli/pathogenicity; Escherichia coli Infections/microbiology; Genes, Bacterial; Humans; Mutagenesis |
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