Histone-like proteins
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In the 1970 and 80s, histone-like proteins in E. coli were defined on the basis of being small, basic, DNA-binding proteins.[1] need add'l ref Some of these, such as HU and H-NS, share the function of compacting chromosomal DNA with histones, but are not homologous to histones.
HU
H-NS
Stp
HlpA
HlpA (histone-like protein A) [2] Later shown to be a periplasmic protein chaperone, Skp.
- ↑ Rouvière-Yaniv, J & Gros, F (1975) Characterization of a novel, low-molecular-weight DNA-binding protein from Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 72 3428-32 PubMed
- ↑ Lathe, R et al. (1980) Prokaryotic histone-like protein interacting with RNA polymerase. Proc. Natl. Acad. Sci. U.S.A. 77 3548-52 PubMed