Gene Ontology (GO)
You can help EcoliWiki by editing the content of this page. For information about becoming a registered user and obtaining editing privileges, see Help:Accounts.
Provides a controlled vocabulary to describe gene and gene product attributes in any organism.
About Gene Ontology (GO)
The Gene Ontology Project sets a vocabulary standard to describe gene and gene products so comparisons may be made across species.
Organizing Principles of GO:
- cellular component
- biological process
- molecular function
The Gene Ontology website can be thought of as a set of interlinked sites:
- The Gene Ontology Consortium website. The main website has resources and official documentation for the project.
- project wiki mostly for internal discussions
- Sourceforge pages for ontology requests and other support
Using Gene Ontology (GO)
This section mostly describes using AmiGO
Input: Gene name
Output: GO terms relating to the different species
Add links to additional pages describing success stories here.
Many websites have their own GO browsers, and/or tools to examine GO annotations for genes. A list can be found at tools page at the GO website. Examples
- GONUTS, the Gene Ontology Normal Usage Tracking System is a wiki-based system for capturing community usage notes for GO terms and for doing annotation of protein-encoding genes. GONUTS is not an official GO consortium site, but it supports annotation jamborees from the GO Reference Genomes project. GO term pages on AmiGO link to GONUTS and vice versa.
- Ontology Lookup Service at EBI.
See Help:References for how to manage references in EcoliWiki.
Gene Ontology: tool for the unification of biology. THe Gene Ontology Consortium (2000) Nature Genetics. 25: 25-29.