ExPASy proteomics server

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Analysis of protein sequences and structures.


Swiss Institute for Bioinformatics


Last Updated: Aug 2008

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About ExPASy proteomics server

The ExPASy proteomics server is the site people mean when they talk about SwissProt. In fact, the website is a portal to several proteome-related services provided by the Swiss Institute for Bioinformatics in collaboration, in many cases, with the European Bioinformatics Institute (EBI).


Major database components of the ExPASy proteomics server include:

  • UniProt KnowledgeBase (EcoliWiki Page) :a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases.
  • SWISS-MODEL (EcoliWiki Page):a database of annotated three-dimensional comparative protein structure models generated by the fully automated homology-modelling pipeline SWISS-MODEL.
  • SWISS-2DPAGE :contains data on proteins identified on various 2-D PAGE and SDS-PAGE reference maps.
  • ENZYME :a repository of information relative to the nomenclature of enzymes.

Expasy also provides many online software tools.

Using ExPASy proteomics server



query by Swiss-Prot# (http://ca.expasy.org/cgi-bin/get-entries?AC=P25530)
EC# mapped to b# (http://us.expasy.org/cgi-bin/nicezyme.pl?

Usage examples

Add links to additional pages describing success stories here.

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Web Services/API



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External Links

ExPASy proteomics server URL: http://www.expasy.org

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