E. coli as a model organism

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E. coli is arguable the best studied free-living organism. A substantial fraction of our knowledge of fundamentally conserved biological processes at the molecular level derives from experiments done in laboratory E. coli and its symbionts. This includes information related to the function of orthologous genes in humans, plants, and animals of economic and medical importance.

E. coli and basic research

microbial genetics


bacterial physiology

artificial evolution

E. coli and biotechnology

E. coli and the recombinant DNA revolution

Industrial importance

Synthetic biology

See also

  • wikipedia:Escherichia_coli_(molecular_biology)
  • Microcosm - Carl Zimmer's book about the importance of E. coli
  • Phage and the Origins of Molecular Biology
  • Eighth Day of Creation - Horace Freeland Judson's history of the beginnings of molecular biology
  • Operators and Promoters - Hatch Echols' history of molecular biology