Cephalexin

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Inhibits septation by blocking FtsI transpeptidase activity, but does not affect the overall organization of the septum over short periods of time[1][2].

References

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  1. Pogliano, J et al. (1997) Inactivation of FtsI inhibits constriction of the FtsZ cytokinetic ring and delays the assembly of FtsZ rings at potential division sites. Proc. Natl. Acad. Sci. U.S.A. 94 559-64 PubMed
  2. Kennedy, SP et al. (2008) Delayed activation of Xer recombination at dif by FtsK during septum assembly in Escherichia coli. Mol. Microbiol. 68 1018-28 PubMed