Category:Complex:methylcitrate synthase

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Description (originally from EcoCyc[1]) methylcitrate synthase

Comments (originally from EcoCyc[1]) The prpC-encoded protein is a methylcitrate synthase with citrate synthase activity as a minor component. The enzyme is distinct from the gltA-encoded citrate synthase. Methylcitrate synthase is induced during growth on propionate and catalyzes a reaction in propionate metabolism via the methylcitrate cycle. [2][3][4][5]


References

  1. 1.0 1.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  2. Gerike, U et al. (1998) Citrate synthase and 2-methylcitrate synthase: structural, functional and evolutionary relationships. Microbiology (Reading, Engl.) 144 ( Pt 4) 929-35 PubMed
  3. Patton, AJ et al. (1993) Does Escherichia coli possess a second citrate synthase gene? Eur. J. Biochem. 214 75-81 PubMed
  4. London, RE et al. (1999) Carbon-13 nuclear magnetic resonance study of metabolism of propionate by Escherichia coli. J. Bacteriol. 181 3562-70 PubMed
  5. Textor, S et al. (1997) Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria. Arch. Microbiol. 168 428-36 PubMed

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