Category:Complex:gamma-glutamyl kinase

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Description (originally from EcoCyc[1][2]) γ-glutamyl kinase

Comments (originally from EcoCyc[1][2]) Glutamate 5-kinase catalyzes the first reaction in the synthesis of proline and is coded for by the gene proB. The second reaction is catalyzed by glutamate-5-semialdehyde dehydrogenase, coded for by the proA gene. It has been determined that these two enzymes form a complex and that the presence of GSA dehydrogenase is necessary for the glutamate 5-kinase activity. [3]


References

  1. 1.0 1.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  2. 2.0 2.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. Smith, CJ et al. (1984) Purification and characteristics of a gamma-glutamyl kinase involved in Escherichia coli proline biosynthesis. J. Bacteriol. 157 545-51 PubMed

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