Category:Complex:FruR transcriptional dual regulator
About
Description (originally from EcoCyc[1][2]) FruR transcriptional dual regulator
Comments (originally from EcoCyc[2]) FruR is a dual transcriptional regulator that is implicated in the regulation of a large number of operons that encode enzymes, which comprise central pathways of carbon metabolism. It represses some operons (nirBDC-cysG, fruBKA, ptsHI-crr, and edd-eda) but activates others (aceBAK, icdA, pckA, and ppsA). It belongs to the GalR/LacI family of transcriptional regulators.
Cra was formerly known as FruR. Protein Complex FruR site length 14.
The wild-type Cra (FruR) protein binds to DNA as a homotetramer.
A microarray analysis for FruR of Escherichia coli was done by [3].
References
- ↑ EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 2.0 2.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Perrenoud, A & Sauer, U (2005) Impact of global transcriptional regulation by ArcA, ArcB, Cra, Crp, Cya, Fnr, and Mlc on glucose catabolism in Escherichia coli. J. Bacteriol. 187 3171-9 PubMed
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