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Description (originally from EcoCyc[1]) DnaT

Comments (originally from EcoCyc[1]) DnaT is required for chromosomal DNA replication and for induction of replication in the absence of protein synthesis during the SOS response [2][3][4][5][6][7][8][9][10][11][8][12][13].


  1. 1.0 1.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  2. Lark, CA et al. (1978) dnaT, dominant conditional-lethal mutation affecting DNA replication in Escherichia coli. J. Bacteriol. 136 1008-17 PubMed
  3. Masai, H et al. (1986) Cloning of the Escherichia coli gene for primosomal protein i: the relationship to dnaT, essential for chromosomal DNA replication. Proc. Natl. Acad. Sci. U.S.A. 83 1256-60 PubMed
  4. Arai, K et al. (1981) Purification and properties of Escherichia coli protein i, a prepriming protein in phi X174 DNA replication. J. Biol. Chem. 256 5281-6 PubMed
  5. Allen, GC Jr & Kornberg, A (1993) Assembly of the primosome of DNA replication in Escherichia coli. J. Biol. Chem. 268 19204-9 PubMed
  6. Liu, J et al. (1996) The ordered assembly of the phiX174-type primosome. III. PriB facilitates complex formation between PriA and DnaT. J. Biol. Chem. 271 15656-61 PubMed
  7. Heller, RC & Marians, KJ (2005) The disposition of nascent strands at stalled replication forks dictates the pathway of replisome loading during restart. Mol. Cell 17 733-43 PubMed
  8. 8.0 8.1 Masai, H & Arai, K (1989) Escherichia coli dnaT gene function is required for pBR322 plasmid replication but not for R1 plasmid replication. J. Bacteriol. 171 2975-80 PubMed
  9. Masai, H & Arai, K (1988) Initiation of lagging-strand synthesis for pBR322 plasmid DNA replication in vitro is dependent on primosomal protein i encoded by dnaT. J. Biol. Chem. 263 15016-23 PubMed
  10. Scherzinger, E et al. (1991) Plasmid RSF1010 DNA replication in vitro promoted by purified RSF1010 RepA, RepB and RepC proteins. Nucleic Acids Res. 19 1203-11 PubMed
  11. Allen, GC Jr et al. (1993) Strand switching of a replicative DNA helicase promoted by the E. coli primosome. Cell 74 713-22 PubMed
  12. Yang, H et al. (2004) Identification of mutator genes and mutational pathways in Escherichia coli using a multicopy cloning approach. Mol. Microbiol. 53 283-95 PubMed
  13. Antony, T et al. (1996) Effects of Mg2+ and denaturants on the unfolding pattern of DNA-T--a replication protein of E. coli. Int. J. Biol. Macromol. 19 91-7 PubMed

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