Comments (originally from EcoCyc) The enzyme carries out reactions in in the pathways of both the biosynthesis of isoleucine and of valine. Dihydroxy-acid dehydratase contains a [4Fe-4S] cluster which is essential for catalysis and unstable in the presence of O2 and O(-)2. 
- EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- Flint, DH et al. (1993) The role and properties of the iron-sulfur cluster in Escherichia coli dihydroxy-acid dehydratase. J. Biol. Chem. 268 14732-42 PubMed
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