Category:Complex:D-alanine-D-alanine ligase B
About
Description (originally from EcoCyc[1][2]) D-alanine-D-alanine ligase B
Comments (originally from EcoCyc[1][2]) There are two distinct D-alanine-D-alanine ligase activites in E. coli. One is coded for by the ddlA gene and the second by the ddlB gene. D-alanine-D-alanine ligase, along with alanine racemase, makes up the D-alanine branch of peptidoglycan biosynthesis. The enzyme synthesizes D-alanyl-D-alanine from two molecules of D-alanine, which is then added to the growing cell wall precursor. [3].
References
- ↑ 1.0 1.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 2.0 2.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Zawadzke, LE et al. (1991) Existence of two D-alanine:D-alanine ligases in Escherichia coli: cloning and sequencing of the ddlA gene and purification and characterization of the DdlA and DdlB enzymes. Biochemistry 30 1673-82 PubMed
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