Category:Complex:3-methyl-2-oxobutanoate hydroxymethyltransferase

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Description (originally from EcoCyc[1][2]) 3-methyl-2-oxobutanoate hydroxymethyltransferase

Comments (originally from EcoCyc[1][2]) 3-methyl-2-oxobutanoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step of the pantothenate biosynthesis pathway. The product of the reaction, dehydropantoate is an essential precursor of pantothenate [3][3]


References

  1. 1.0 1.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  2. 2.0 2.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 Powers, SG & Snell, EE (1976) Ketopantoate hydroxymethyltransferase. II. Physical, catalytic, and regulatory properties. J. Biol. Chem. 251 3786-93 PubMed

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