hha:Quickview

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Standard Name

hha

Gene Synonym(s)

ECK0454, b0460, JW0449[1]

Product Desc.

haemolysin expression modulating protein[2][3]

Modulates hemolysin expression, in complex with H-NS; stimulates transposition events; induced by AI-2 pheromone; promotes conjugation and conjugation-induced biofilms[4]

Product Synonyms(s)

modulator of gene expression, with H-NS[1], B0460[2][1], Hha[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): hha[2]

Regulation/Activity


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Notes

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Hha and Cnu are paralogs. The expression of the hly operon of plasmid pHly152 is modulatedby Hha/HN-S. Overexpression of Cnu(YdgT) partially suppresses the hha defect on hylA expression. Hha positively modulates H-NS expression. Induced during biofilm formation.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.