dcm:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

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Standard Name
Gene Synonym(s)
Product Desc.
Product Synonyms(s)
Knock-Out Phenotype
Regulation/Expression
Regulation/Activity
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Notes

Method of Mutagenesis: Log-phase cultures of strain GM 1 were treated with Alkylating agent (N-methyl-N-nitro-nitrosoguanidine)[1]


Phenotype Observed: Mutants were tested for S-adenosylmethionine methyltransferase activity by measuring the levels of DNA-cytosine (S-adenosylmethionine and DNA-adenine. The mutants showed reduced or absent activity. Also, deficient in methylcytosine in DNA. [1]


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References

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  1. ↑ 1.0 1.1 Marinus, MG & Morris, NR (1973) Isolation of deoxyribonucleic acid methylase mutants of Escherichia coli K-12. J. Bacteriol. 114 1143-50 PubMed