chbR:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
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Standard Name
Gene Synonym(s)
Product Desc.
Product Synonyms(s)
Knock-Out Phenotype
Regulation/Expression
Regulation/Activity
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Notes

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ChbR was initially reported as a repressor of the chb operon. However later work showed that this protein is an activator as well as the repressor of the chb operon. The mutations in the chbR have also been reported to confer Cel+ phenotype to E. coli.

References

[1] [2] [3]

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  1. ↑ Kachroo, AH et al. (2007) Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose. Mol. Microbiol. 66 1382-95 PubMed
  2. ↑ Plumbridge, J & Pellegrini, O (2004) Expression of the chitobiose operon of Escherichia coli is regulated by three transcription factors: NagC, ChbR and CAP. Mol. Microbiol. 52 437-49 PubMed
  3. ↑ Keyhani, NO & Roseman, S (1997) Wild-type Escherichia coli grows on the chitin disaccharide, N,N'-diacetylchitobiose, by expressing the cel operon. Proc. Natl. Acad. Sci. U.S.A. 94 14367-71 PubMed