cmoA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Gene Name | |
|---|---|
| Product(s) |
YecO product[1]: predicted methyltransferase product, B1870 product, CmoA product, CmoB product |
| Description |
putative methyltransferase[3] predicted methyltransferase[2] |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity |
|
| edit table |
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Notes
CmoA catalyzes an intermediate step(s) in tRNA(cmo5U34) and tRNA(mcmo5U34) synthesis that forms uridine-5-oxyacetic acid (cmo5U) and uridine-5-oxyacetic acid methyl ester (mcmo5U) in tRNA. The cmoA ortholog is functionally characterized in S. typhimurium. YecO is paralogous to YgdE and FtsJ. otherPDB (H. influenzae): 1IM8. Modeling of 1IM8 suggests substrate might be a benzoic acid derivative, possibly consistent with a chorismic acid requirement for the synthesis of cmo(5)U34.[4]
References
- ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.