sapD:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Gene Name | |
|---|---|
| Product(s) |
SapD product[1]: predicted antimicrobial peptide transporter subunit product, ATP-binding component of ABC superfamily product, B1291 product, TrkE product |
| Description |
Component of peptide uptake ABC transporter[2] |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity |
|
| edit table |
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Notes
Overexpression causes filamentous biofilm formation. SapD(TrkE) is required for TrkAH activity and stimulates TrkAG transport rate (Bossemeyer, 1989; Dosch, 1991; Harms, 2001). Characterized initially in Salmonella. The proposal that the sap operon transports peptides (Groisman, 1992) has been challenged (Stumpe, 1997; Harms, 2001). SapA ATP-binding, but not hydrolysis, is required for stimulation of Trk (Harms, 2001).[4]
References
- ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.