prfC:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

prfC (synonyms: ECK4366, b4375, JW5873, tos, miaD)[1]

Product(s)

PrfC product[1]: peptide chain release factor RF-3 product, B4375 product, Tos product, MiaD product

Description

peptide chain release factor RF3[2][3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): prfC[2]

Regulation/Activity


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Notes

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RF3 exits in two conformational states, state 1 which is a pre-translocation complex with a P-site tRNA and a pre-bound RF3 (inactive) while state 2 is a post-translocation conformation with RF3 tightly bound to the GTPase centre and the tRNA at the exit site. RF-3 is a class 2 RF, and a G-protein.[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.