hdeA:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

hdeA (synonyms: ECK3494, b3510, JW3478, yhhC, yhiB)[1]

Product(s)

HdeA product[1]: stress response protein acid-resistance protein product, B3510 product, YhhC product, YhiB product

Description

acid-resistance protein, possible chaperone[2][3]

Component of HdeA dimer, inactive form of acid-resistance protein[3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): hdeAB[2]

Regulation/Activity


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Notes

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Overexpression causes abnormal biofilm architecture. Acid-inducible and important for acid survival. HdeA and HdeB are both involved in periplasmic protein solubilization at pH 3; HdeA is involved in periplasmic protein solubilization at pH 2 (Kern, 2006).[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.