gltX:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

gltX (synonyms: ECK2394, b2400, JW2395, gltM, gluRS, G259)[1][2]

Product(s)

GltX product[1]: glutamyl-tRNA synthetase product, B2400 product, GltM product

Description

GLURS-MONOMER[2][3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): gltX[2]

Regulation/Activity


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Notes

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The zinc binding motif Cys98-x-Cys100-x(24)-Cys125-x-H127 of GltX categorizes this as a SWIM domain (standard C-x-C-x(n)-C-x-H with n=6-25). Mutation analysis (C100Y) indicates SWIM plays a minimal role in overall binding of tRNA, but an increased role in orientation of the acceptor 3?-terminal adenosine.[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.