Clusters of Orthologous Groups (COGs)

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Clusters of Orthologous Groups (COGs)
Who: NCBI
What: Phylogenetic classification of proteins encoded in complete genomes
Where: Clusters of Orthologous Groups (COGs)
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About Clusters of Orthologous Groups (COGs)

The Clusters of Orthologous Groups (COGs) of proteins were generated by comparing the protein sequences of complete genomes. Each cluster contains proteins or groups of paralogs from at least three lineages. The current COG database contains both prokaryotic and eukaryotic clusters.

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References

The COG database: an updated version includes eukaryotes.
Tatusov RL 'et al' BMC Bioinformatics. 2003 Sep 11;4:41. Epub 2003 Sep 11. Full Text

The COG database: a tool for genome-scale analysis of protein functions and evolution.
Tatusov RL 'et al' Nucleic Acids Res. 2000 Jan 1;28(1):33-6. Full Text

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Clusters of Orthologous Groups (COGs)

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