PMID:3413113
| Citation |
Henikoff, S, Haughn, GW, Calvo, JM and Wallace, JC (1988) A large family of bacterial activator proteins. Proc. Natl. Acad. Sci. U.S.A. 85:6602-6 |
|---|---|
| Abstract |
At least nine different bacterial proteins belong to the LysR family. The gene sequence for one of these proteins is presented here. Six others (Escherichia coli LysR, IlvY, CysB; Salmonella typhimurium MetR; Rhizobium NodD; and Enterobacter cloacae AmpR) are known to activate other genes. Based on sequence alignments, each member of this family is predicted to have a helix-turn-helix DNA binding motif near its amino terminus. The combined evidence indicates that all nine proteins are related by common ancestry, are similarly folded, and are not detectably related to other known bacterial regulatory proteins. The DNA database searching procedure and other methods used in this study should be useful in detecting other groups of related proteins. |
| Links | |
| Keywords |
Bacterial Proteins/analysis; Bacterial Proteins/genetics; Base Sequence; DNA, Bacterial/analysis; DNA, Bacterial/metabolism; Enterobacteriaceae/analysis; Information Systems; Molecular Sequence Data |
| edit table |
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
<annotationlinks/>
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
References
See Help:References for how to manage references in EcoliWiki.