cobB:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Standard Name |
cobB |
|---|---|
| Gene Synonym(s) |
ECK1106, b1120, JW1106, ycfY[1], npdA, ycfY |
| Product Desc. |
protein deacetylase, Sir2 homolog[2][3] Sirtuin lysine deacetylase for acetyl-CoA synthetase, NAD-dependent; partial cobalamin biosynthesis pathway present in E. coli[4] |
| Product Synonyms(s) |
deacetylase of acetyl-CoA synthetase, NAD-dependent[1], B1120[2][1], YcfY[2][1], CobB[2][1] , ECK1106, JW1106, npdA, ycfY, b1120 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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Notes
CobB is primarily characterized in Salmonella (Starai, 2002). CobB may be responsible for additional lysine deacetylations since it is the only sirtuin homolog; Pat may be the general protein acetylase. A large number of lysines are acetylated and deacetylated in E. coli; presumably many or all of them by Pat/CobB (Yu, 2008; Zhang, 2008).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.