Bicyclomycin

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to add a reference: Genes in E. coli that affect sensitivity to bicyclomycin.[1]


Mode of Action

Structure

Targets

Bicyclomycin targets the transcription termination factor Rho [2]

Mechanisms of Resistance

Mutations that affect sensitivity

Gene Allele Sensitivity to BCM Reference



References

See Help:References for how to manage references in EcoliWiki.

  1. ↑ Tran, L et al. (2011) Single-gene deletion mutants of Escherichia coli with altered sensitivity to bicyclomycin, an inhibitor of transcription termination factor Rho. J. Bacteriol. 193 2229-35 PubMed
  2. ↑ Zwiefka, A et al. (1993) Transcription termination factor rho: the site of bicyclomycin inhibition in Escherichia coli. Biochemistry 32 3564-70 PubMed