glnD:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''glnD''  
''glnD''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK0165, b0167, JW0162, glnD5''<ref name='LIB:Riley_2006'/>
''ECK0165, b0167, JW0162, glnD5''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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GLND<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
GLND<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Bifunctional uridylyltransferase/uridylyl-removing enzyme; (UTase/UR); controls uridylylation state and activity of PII(GlnB)<ref name='LIB:EcoGene'/>
Bifunctional uridylyltransferase/uridylyl-removing enzyme; (UTase/UR); controls uridylylation state and activity of PII(GlnB)<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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uridylyltransferase<ref name='LIB:Riley_2006'/>, B0167<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GlnD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
uridylyltransferase<ref name='LIB:Riley_2006'/>, B0167<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GlnD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:dapD|dapD]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:dapD|dapD]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 01:21, 9 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

glnD

Gene Synonym(s)

ECK0165, b0167, JW0162, glnD5[1]

Product Desc.

GLND[2][3]

Bifunctional uridylyltransferase/uridylyl-removing enzyme; (UTase/UR); controls uridylylation state and activity of PII(GlnB)[4]

Product Synonyms(s)

uridylyltransferase[1], B0167[2][1], GlnD[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): dapD[2]

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


GlnD has both a uridylyltransferase and a uridylyl-removing activity. The only known substrates for GlnD are the two PII proteins GlnB and GlnK. In both cases GlnD covalently modifies residue Tyr51 in the T-loop of the substrate thereby controlling the ability of GlnB and GlnK to interact with their specific targets. The activity of GlnD is controlled by the intracellular glutamine availability. Glutamine inhibits the transferase action of GlnD and as a consequence GlnB and GlnK are deuridylylated in N-sufficient conditions. [Comment provided by EcoTeam member Mike Merrick, 11.16.06][4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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