hflC:Quickview: Difference between revisions
imported>Wikientrybot No edit summary |
imported>Wikientrybot No edit summary |
||
| Line 28: | Line 28: | ||
|- | |- | ||
!align=left {{table_heading_style}} |Standard Name | !align=left {{table_heading_style}} |Standard Name | ||
|| | |||
''hflC'' | |||
|- | |- | ||
!align=left {{table_heading_style}} |Gene Synonym(s) | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
|| | |||
''ECK4171, b4175, JW4133, hflA''<ref name='LIB:Riley_2006'/> | |||
|- | |- | ||
!align=left {{table_heading_style}} |Product Desc. | !align=left {{table_heading_style}} |Product Desc. | ||
|| | |||
regulator of FtsH protease<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | |||
Component of [[:Category:Complex:HflK-HflC complex; regulator of FtsH protease|HflK-HflC complex; regulator of FtsH protease]]<ref name='LIB:EcoCyc11.1'/>; [[:Category:Complex:HflB, integral membrane ATP-dependent zinc metallopeptidase|HflB, integral membrane ATP-dependent zinc metallopeptidase]]<ref name='LIB:EcoCyc11.1'/> | |||
Membrane bound protease complex, with FtsH and HflK; regulates lysogeny; non-essential<ref name='LIB:EcoGene'/> | |||
|- | |- | ||
!align=left {{table_heading_style}} |Product Synonyms(s) | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
|| | |||
modulator for HflB protease specific for phage lambda cII repressor product<ref name='LIB:Riley_2006'/>, B4175 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HflA product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HflC product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | |||
|- | |- | ||
!align=left {{table_heading_style}} |Knock-Out Phenotype | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
|| | |||
|- | |- | ||
!align=left {{table_heading_style}} |Regulation/Expression | !align=left {{table_heading_style}} |Regulation/Expression | ||
|| | |||
transcription unit(s): [[:Category:Txn_unit:yjeFE-amiB-mutL-miaA-hfq-hflXKC|yjeFE-amiB-mutL-miaA-hfq-hflXKC]]<ref name='LIB:EcoCyc10.6'/>, ORF55-ORF17-amiB-mutL-miaA-hfq-hflXKC | |||
|- | |- | ||
!align=left {{table_heading_style}} |Regulation/Activity | !align=left {{table_heading_style}} |Regulation/Activity | ||
|| | |||
|-class='sortbottom' | |-class='sortbottom' | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=bc145ea147f7e36caf09c1bfeed4ee9d.10102.V49aee8abdac57&page=10102&pagename={{FULLPAGENAMEE}}&type=1&template=New_Quickview_Table edit table] | |[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=bc145ea147f7e36caf09c1bfeed4ee9d.10102.V49aee8abdac57&page=10102&pagename={{FULLPAGENAMEE}}&type=1&template=New_Quickview_Table edit table] || | ||
|} | |} | ||
<!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.10102.V49aee8abdac57--></protect> | <!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.10102.V49aee8abdac57--></protect> | ||
Revision as of 20:46, 4 March 2009
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
hflC |
|---|---|
| Gene Synonym(s) |
ECK4171, b4175, JW4133, hflA[1] |
| Product Desc. |
regulator of FtsH protease[2][3]; Component of HflK-HflC complex; regulator of FtsH protease[3]; HflB, integral membrane ATP-dependent zinc metallopeptidase[3] Membrane bound protease complex, with FtsH and HflK; regulates lysogeny; non-essential[4] |
| Product Synonyms(s) |
modulator for HflB protease specific for phage lambda cII repressor product[1], B4175 product[2][1], HflA product[2][1], HflC product[2][1] |
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): yjeFE-amiB-mutL-miaA-hfq-hflXKC[2], ORF55-ORF17-amiB-mutL-miaA-hfq-hflXKC |
| Regulation/Activity |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
Gain-of-function alleles in hflC and hflK inhibit FtsH-mediated degradation of uncomplexed SecY protein and other membrane protein substrates. Null hflC or hflK alleles stabilize cytoplasmic substrate cII. hflCK is a multicopy suppressor of ftsH htpX double mutant. Serine protease-like motif in HflC not required for cII degradation. HflC and HflK have a periplasmic prohibitin homology (PHB) domain. HT_Cmplx45_Mem: HflC+HybC+BamB.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.