nrdD:Quickview: Difference between revisions

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===Notes===
===Notes===
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Activated NrdD is predicted to be cleaved by oxygen at the Gly681 radical, dropping the last 31 aa.  Requires AdoMet for oxidation of the iron-sulfur center and glycine radical formation. FNR regulon. Binds TrxA (Kumar, 2004).<ref name='LIB:EcoGene'/>





Revision as of 01:10, 3 March 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

nrdD (synonyms: ECK4233, b4238, JW4197)[1]

Product(s)

NrdD product[1]: anaerobic ribonucleoside-triphosphate reductase product, B4238 product

Description

ribonucleoside-triphosphate reductase[2][3]

Component of ribonucleoside-triphosphate reductase[2],anaerobic nucleoside-triphosphate reductase activating system[2]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): nrdDG[2]

Regulation/Activity


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Notes

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Activated NrdD is predicted to be cleaved by oxygen at the Gly681 radical, dropping the last 31 aa. Requires AdoMet for oxidation of the iron-sulfur center and glycine radical formation. FNR regulon. Binds TrxA (Kumar, 2004).[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.