alkB:Quickview: Difference between revisions

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===Notes===
===Notes===
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AlkB mutants are extremely sensitive to MMS. Also repairs alkylated mRNA and tRNA in vivo and in vitro, the first example of direct RNA repair. Repairs epsilonA and epsilonC. Ada regulon.<ref name='LIB:EcoGene'/>





Revision as of 23:23, 2 March 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

alkB (synonyms: ECK2204, b2212, JW2200, aidD)[1]

Product(s)

AlkB product[1]: oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions product, B2212 product, AidD product

Description

AlkB repair system for alkylated DNA and RNA[2][3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ada-alkB[2], OP00100, alkB[2]

Regulation/Activity


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See Help:Quickview for help with entering information in the Quickview table.

Notes

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AlkB mutants are extremely sensitive to MMS. Also repairs alkylated mRNA and tRNA in vivo and in vitro, the first example of direct RNA repair. Repairs epsilonA and epsilonC. Ada regulon.[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.