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Revision as of 07:55, 30 April 2008

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

nudH (synonyms: ECK2826, b2830, JW2798, ydgP, ygdP)[1]

rppH [2]

Product(s)

NudH product[1]: nucleotide hydrolase product, B2830 product, YgdP product

RNA pyrophophohydrolase

Description

putative invasion protein[3][4]

Removes 5'-pyrophosphate from mRNAs and initiates degradation by the 5'-end dependent pathway. [2]

Knock-Out Phenotype

Many mRNAs have increased t1/2. [2]

Regulation/Expression

transcription unit(s): ptsP[3]

Regulation/Activity
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Notes

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References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 Deana, A et al. (2008) The bacterial enzyme RppH triggers messenger RNA degradation by 5' pyrophosphate removal. Nature 451 355-8 PubMed
  3. ↑ 3.0 3.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7