mtgA:Quickview: Difference between revisions
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!align=left {{table_heading_style}} |Gene Synonym(s) | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK3197, b3208, JW3175, yrbM, mgt''<ref name='LIB:Riley_2006'/> | ''ECK3197, b3208, JW3175, yrbM, mgt''<ref name='LIB:Riley_2006'/>, mgt'' | ||
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!align=left {{table_heading_style}} |Product Desc. | !align=left {{table_heading_style}} |Product Desc. | ||
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!align=left {{table_heading_style}} |Product Synonyms(s) | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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biosynthetic peptidoglycan transglycosylase<ref name='LIB:Riley_2006'/>, B3208<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mgt<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YrbM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MtgA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ''biosynthetic peptidoglycan transglycosylase<ref name='LIB:Riley_2006'/>, B3208<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mgt<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YrbM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MtgA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3197, JW3175, mgt, yrbM, b3208'' | ||
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!align=left {{table_heading_style}} |Function from GO | !align=left {{table_heading_style}} |Function from GO | ||
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!align=left {{table_heading_style}} |Quick Links | !align=left {{table_heading_style}} |Quick Links | ||
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[http://porteco.org/AjaxSearch.jsp?searchString=mtgA&s=search | [[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=mtgA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=G7668]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120004215&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=mtgA&loc=MG1655%3A3347831..3347103,W3110%3A3349664..3348936,DH10B%3A3445576..3444848,REL606%3A3285044..3284316,BW2952%3A3234251..3234979]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3234251&end=3234979&gene=mtgA&aa=msksrltvfsfvrrfllrlmvvlavfwgggialfsvapvpfsavmverqvsawlhgnfryvahsdwvsmdqispwmglaviaaedqkfpehwgfdvasiekalahnernenrirgastisqqtaknlflwdgrswvrkgleagltlgietvwskkriltvylniaefgdgvfgveaaaqryfhkpaskltrseaallaavlpnplrfkvsspsgyvrsrqawilrqmyqlggepfmqqhqld]] [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=mtgA+AND+escherichia+coli]] [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=mtgA]] | ||
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Latest revision as of 21:47, 27 May 2013
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Standard Name |
mtgA |
|---|---|
| Gene Synonym(s) |
ECK3197, b3208, JW3175, yrbM, mgt[1], mgt |
| Product Desc. |
biosynthetic peptidoglycan transglycosylase[2][3] Monofunctional peptidoglycan glycosyltransferase; monofunctional biosynthetic peptidoglycan transglycosylase; GTase; TGase[4] |
| Product Synonyms(s) |
biosynthetic peptidoglycan transglycosylase[1], B3208[2][1], Mgt[2][1], YrbM[2][1], MtgA[2][1] , ECK3197, JW3175, mgt, yrbM, b3208 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
MtgA has flavomycin-resistant peptidoglycan synthesis activity (Di Berardino, 1996 [5]; Derouaux, 2007). mtgA is a non-essential gene (Schiffer, 1999). MtgA localizes to the division site and interacts with FtsW, FtsN, and FtsI in mcrA(Ts) mrcB- strains, indicating a role for MtgA in peptidoglycan synthesis related to the cell cycle (Derouaux, 2007). The use of the term transglycolase is ambiguous as it can describe both lytic and synthetic peptidoglycan activities, therefore glycosyltransferase is preferred (Di Berardino, 1996). MtgA lacks a penicillin binding domain and therefore is penicillin-insensitive. MtgA is a membrane-bound periplasmic enzyme that has an uncleaved signal anchor (Di Berardino, 1996). MtgA may be the glycan polymerase characterized by Hara (1984), although it has an apparent MW larger than MtgA (Di Berardino, 1996).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Di Berardino, M et al. (1996) The monofunctional glycosyltransferase of Escherichia coli is a member of a new class of peptidoglycan-synthesising enzymes. FEBS Lett. 392 184-8 PubMed