PMID:21421753: Difference between revisions

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<span style = 'font-size: large'> '''Foti, JJ and Walker, GC'''  (2011) Efficient extension of slipped DNA intermediates by DinB is required to escape primer template realignment by DnaQ.''J. Bacteriol.'' '''193''':2637-41</span>


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|{{TableHeadingColor}} |'''Abstract''' || <protect>We show that Escherichia coli DinB polymerase, which creates single-base deletions, prefers to extend slipped DNA substrates with the skipped base at the -4 position. A DinB(Y79L) variant, which extends these substrates less efficiently in vitro, allows the proofreading function of polymerase III to reverse their formation in vivo.</protect>
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*  [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=21421753 PubMed]
Online version:[http://dx.doi.org/10.1128/JB.00005-11 10.1128/JB.00005-11]
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Revision as of 22:12, 9 August 2011

Foti, JJ and Walker, GC (2011) Efficient extension of slipped DNA intermediates by DinB is required to escape primer template realignment by DnaQ.J. Bacteriol. 193:2637-41

Abstract <protect>We show that Escherichia coli DinB polymerase, which creates single-base deletions, prefers to extend slipped DNA substrates with the skipped base at the -4 position. A DinB(Y79L) variant, which extends these substrates less efficiently in vitro, allows the proofreading function of polymerase III to reverse their formation in vivo.

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Online version:10.1128/JB.00005-11 |} </protect>

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