PMID:12374860: Difference between revisions
Jump to navigation
Jump to search
Update TableEdit tables. |
/Volumes/r3/t3/ul/working/touchTables/touch_all_tables.php |
||
| Line 25: | Line 25: | ||
****************************************************************************************** --> | ****************************************************************************************** --> | ||
{| id="Y4b3eea5a03e25" class=" tableEdit GO_table_reference" | {| id="Y4b3eea5a03e25" class=" tableEdit GO_table_reference" | ||
|- | |- {{table heading style}} | ||
!|Gene product!!Qualifier!!GO ID!!GO term name!!Evidence Code!!with/from!!Aspect!!Notes!!Status | !|Gene product!!Qualifier!!GO ID!!GO term name!!Evidence Code!!with/from!!Aspect!!Notes!!Status | ||
| Line 42: | Line 42: | ||
****************************************************************************************** --> | ****************************************************************************************** --> | ||
{| id="U4b3eea64ea3cd" class=" tableEdit Array_paper_table" | {| id="U4b3eea64ea3cd" class=" tableEdit Array_paper_table" | ||
|- | |- {{table_heading_style}} | ||
!|Accessions!!SMD Category!!SMD Subcategory!!SMD status | !|Accessions!!SMD Category!!SMD Subcategory!!SMD status | ||
Revision as of 20:04, 17 June 2010
Tani, TH, Khodursky, A, Blumenthal, RM, Brown, PO and Matthews, RG (2002) Adaptation to famine: a family of stationary-phase genes revealed by microarray analysis.Proc. Natl. Acad. Sci. U.S.A. 99:13471-6
| Abstract | <protect>Bacterial adaptation to nutrient limitation and increased population densities is central to survival and virulence. Surprisingly, <3% of Escherichia coli genes are known to play roles specific to the stationary phase. There is evidence that the leucine-responsive regulatory protein (Lrp) may play an important role in stationary phase, so this study used microarrays representing >98% of E. coli genes to more comprehensively identify those controlled by Lrp. The primary analysis compared isogenic Lrp(+) and Lrp(-) strains in cells growing in steady state in glucose minimal medium, either in the presence or absence of leucine. More than 400 genes were significantly Lrp-responsive under the conditions used. Transcription of 147 genes was lower in Lrp(+) than in Lrp(-) cells whether or not leucine was present; most of these genes were tightly coregulated under several conditions, including a burst of synthesis on transition to stationary phase. This cluster includes 56 of 115 genes already known to play roles in stationary phase. Our results suggest that the actual number of genes induced on entrance into stationary phase is closer to 200 and that Lrp affects nearly three-quarters of them, including genes involved in response to nutrient limitation, high concentrations of organic acids, and osmotic stress. |
|-
|bgcolor='#CCCCFF' nowrap |Links || PubMed
Online version:10.1073/pnas.212510999
|}
</protect>
Significance
You can help EcoliWiki by summarizing why this paper is useful
Useful Materials and Methods
You can help Ecoliwiki by describing the useful materials (strains, plasmids, antibodies, etc) described in this paper.
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| edit table |
| Accessions | SMD Category | SMD Subcategory | SMD status |
|---|---|---|---|
| edit table |
EcoliWiki Links
Add links to pages that link here (e.g. gene, product, method pages)
See also
References
See Help:References for how to manage references in EcoliWiki.