rhmA:Quickview: Difference between revisions
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!align=left {{table_heading_style}} |Standard Name | !align=left {{table_heading_style}} |Standard Name | ||
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''rhmA'' | ''rhmA'' | ||
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!align=left {{table_heading_style}} |Gene Synonym(s) | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK2238, b2245, JW2239''<ref name='LIB:Riley_2006'/> | ''ECK2238, b2245, JW2239'', yfaU<ref name='LIB:Riley_2006'/> | ||
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!align=left {{table_heading_style}} |Product Desc. | !align=left {{table_heading_style}} |Product Desc. | ||
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predicted aldolase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>. Crystal structure shows that | predicted aldolase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>. Crystal structure shows that RhmA is a | ||
metal-dependent class II aldolase belonging | metal-dependent class II aldolase belonging | ||
to the pyruvate/enolpyruvate binding (�/R)8 barrel superfamily.<ref name='PMID:18754683 '/>, Genomic context suggested a 2-dehydro-3-deoxy | to the pyruvate/enolpyruvate binding (�/R)8 barrel superfamily.<ref name='PMID:18754683 '/>, Genomic context suggested a 2-dehydro-3-deoxy | ||
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Functional assignment of YfaW as a L-rhamnonate dehydratase | Functional assignment of YfaW as a L-rhamnonate dehydratase | ||
suggested 2-dehydro-3-deoxy-L-rhamnonate is the | suggested 2-dehydro-3-deoxy-L-rhamnonate is the | ||
physiological substrate of | physiological substrate of RhmA, and enzyme kinetic measurements | ||
support this assignment. | support this assignment. | ||
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!align=left {{table_heading_style}} |Product Synonyms(s) | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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predicted 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase<ref name='LIB:Riley_2006'/>, B2245<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, | predicted 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase<ref name='LIB:Riley_2006'/>, B2245<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RhmA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ||
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!align=left {{table_heading_style}} |Function from GO | !align=left {{table_heading_style}} |Function from GO | ||
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!align=left {{table_heading_style}} |Quick Links | !align=left {{table_heading_style}} |Quick Links | ||
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[http://ecoliwiki.net/tools/display_dna.php?gene= | [http://ecoliwiki.net/tools/display_dna.php?gene=yfaU&loc=MG1655:2356867..2356064,W3110:2363515..2362712,DH10B:2447855..2447052,REL606:2305358..2304555 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2305358&end=2304555&gene=yfaU&aa=mnallsnpfkerlrkgevqiglwlssttaymaeiaatsgydwllidgehapntiqdlyhqlqavapyasqpvirpvegskplikqvldigaqtllipmvdtaeqarqvvsatryppygergvgasvaraarwgrienymaqvndslcllvqvesktaldnldeildvegidgvfigpadlsaslgypdnaghpevqriietsirriraagkaagflavapdmaqqclawganfvavgvdtmlysdaldqrlamfksgkngprikgsy Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=yfaU+AND+escherichia+coli Pubmed(yfaU)] [http://trimer.tamu.edu/cgi-bin/textpresso/dev/search?q=yfaU Textpresso(yfaU)] | ||
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Revision as of 22:27, 2 March 2010
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
rhmA |
|---|---|
| Gene Synonym(s) |
ECK2238, b2245, JW2239, yfaU[1] |
| Product Desc. |
predicted aldolase[2][3]. Crystal structure shows that RhmA is a metal-dependent class II aldolase belonging to the pyruvate/enolpyruvate binding (�/R)8 barrel superfamily.[4], Genomic context suggested a 2-dehydro-3-deoxy sugar aldolase function rather than the 4-hydroxy-2-ketoheptane- 1,7-dioate aldolase function as annotated in the databases based on homology with the related HpcH. Functional assignment of YfaW as a L-rhamnonate dehydratase suggested 2-dehydro-3-deoxy-L-rhamnonate is the physiological substrate of RhmA, and enzyme kinetic measurements support this assignment. Putative HHED aldolase, function unknown[5] |
| Product Synonyms(s) |
predicted 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase[1], B2245[2][1], RhmA[2][1] |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
YfaU is crystallized.[5]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Rea, D et al. (2008) Crystal structure and functional assignment of YfaU, a metal ion dependent class II aldolase from Escherichia coli K12. Biochemistry 47 9955-65 PubMed
- ↑ 5.0 5.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.