bioB:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''bioB''  
''bioB''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK0764, b0775, JW0758, G8004''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''ECK0764, b0775, JW0758, G8004''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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biotin synthase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
biotin synthase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Biotin synthase; dethiobiotin to biotin pathway; iron-sulfur enzyme<ref name='LIB:EcoGene'/>
Biotin synthase; dethiobiotin to biotin pathway; iron-sulfur enzyme<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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biotin synthase<ref name='LIB:Riley_2006'/>, B0775<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BioB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
biotin synthase<ref name='LIB:Riley_2006'/>, B0775<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BioB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Molecular Function'''
* GO:0004076 biotin synthase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0051537 2 iron, 2 sulfur cluster binding ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0051539 4 iron, 4 sulfur cluster binding ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Biological Process'''
* GO:0009102 biotin biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IMP])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:bioBFCD|bioBFCD]]<ref name='LIB:EcoCyc10.6'/>, OP00157  
transcription unit(s): [[:Category:Txn_unit:bioBFCD|bioBFCD]]<ref name='LIB:EcoCyc10.6'/>, OP00157  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=bioB&loc=MG1655:808567..809607,W3110:809766..810806,DH10B:862495..863535,REL606:801970..803010 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=801970&end=803010&gene=bioB&aa=mahrprwtlsqvtelfekplldllfeaqqvhrqhfdprqvqvstllsiktgacpedckycpqssryktgleaerlmeveqvlesarkakaagstrfcmgaawknpherdmpyleqmvqgvkamgleacmtlgtlsesqaqrlanagldyynhnldtspefygniittrtyqerldtlekvrdagikvcsggivglgetvkdraglllqlanlptppesvpinmlvkvkgtpladnddvdafdfirtiavarimmptsyvrlsagreqmneqtqamcfmagansifygckllttpnpeedkdlqlfrklglnpqqtavlagdneqqqrleqalmtpdtdeyynaaal Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=bioB+AND+escherichia+coli Pubmed(bioB)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=bioB Textpresso(bioB)]


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Revision as of 00:09, 22 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

bioB

Gene Synonym(s)

ECK0764, b0775, JW0758, G8004[1][2]

Product Desc.

biotin synthase[2][3];

Component of biotin synthase[2][3]

Biotin synthase; dethiobiotin to biotin pathway; iron-sulfur enzyme[4]

Product Synonyms(s)

biotin synthase[1], B0775[2][1], BioB[2][1]

Function from GO

Molecular Function

Biological Process

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): bioBFCD[2], OP00157

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(bioB)    Textpresso(bioB)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Radical SAM superfamily. BioB contains two distinct Fe-S cluster binding sites, one site accommodates a [2Fe-2S](2+) cluster with partial noncysteinyl ligation, the other site accommodates a [4Fe-4S](2+,+) cluster that binds S-adenosylmethionine (SAM) at a unique Fe site of the [4Fe-4S](2+) cluster and undergoes O(2)-induced degradation via a distinct type of [2Fe-2S](2+) cluster intermediate.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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